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Exercise induced hypervolemia: Role of exercise volume
Author(s) -
Walker James M.,
Nelson W. Bradley,
Hansen Crystelle,
Mack Gary W.
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a811-a
Subject(s) - medicine , blood pressure , hypervolemia , stroke volume , cardiology , intensity (physics) , exercise intensity , mean arterial pressure , blood volume , heart rate , anesthesia , physical therapy , physics , quantum mechanics
We tested the hypothesis that plasma volume (PV) expansion following high intensity intermittent exercise is proportional to the exercise volume (intensity x duration). Eight subjects performed 3 exercise protocols consisting of 4, 6, and 8 bouts of high intensity intermittent exercise (4 min 85% VO 2 max and 5 min recovery). Changes in PV were determined (Hct & Hb) 24 hr after exercise. Cardiovascular function, stroke volume (impedance cardiography, SV), HR, and arterial blood pressure (non‐invasive arm cuff, SBP & DBP) were also assessed before and 24 hr post exercise. After high intensity exercise PV increased by 8.4 ± 1.3 ( p <0.05) and 6.7 ± 1.0 ( p <0.05) for 4 and 6 bouts, respectively. The change in PV after 8 bouts of exercise (4.1 ± 2.1%) was not significant. The increase in PV following 4 bouts was greater than 8 bouts of exercise ( p <0.05). Mean arterial pressure (MAP) decreased from 84 ± 2 to 78 ± 2 mmHg ( p <0.05) while HR also decreased ( p <0.05) following 4 bouts. MAP was lower in the 4x trial than 6x (81 ± 3 mmHg, p <0.05) or 8x (83 ± 2 mmHg, p <0.05) trial. 24 hr post exercise resting SV was similar for all trials. The magnitude of PV expansion following high intensity intermittent exercise reflects an interaction between exercise volume (4x, 6x or 8x) and blood pressure. Specifically, PV expansion was greatest following 4 bouts of high intensity exercise where post‐exercise hypotension was largest. These data support the hypothesis that PV expansion following high intensity exercise is dependent upon the interaction of stimuli related to exercise intensity and post‐exercise hypotension. Funded by NIH HL‐020634.