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THE EFFECT OF CHROMIUM (VI) OXIDE ‐ CrO3 ‐ ON THE DURATION OF Drosophila melanogaster PREADULT DEVELOPMENT
Author(s) -
Bajraktari Ismet Dervish,
Alija Avdulla J.,
Muharremi Hidajete S.,
Halili Fetah M.,
Gashi Agim M.
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a642-b
Subject(s) - chromium , drosophila melanogaster , heterozygote advantage , genetics , biology , chromosome , mutation , wild type , chromium oxide , oxide , recombination , chemistry , gene , allele , mutant , organic chemistry
In this study we investigated the effect of chromium (VI) oxide ‐ CrO3 ‐ on genes controlling the duration of wild type Drosophila melanogaster preadult development. The second chromosome of wild type flies was isolated and transferred either in homozygous ( +’ / +’ ) or heterozygous ( +’ / +’’ ) state using the Cy/Pm line. Individuals of this line contain dominant mutations (Cy – Curly wings and Pm – Plum eyes) and long inversions, which prevent recombination with analysed chromosomes, with the end result of stable heredity in the descendants. The +/+ flies were fed varying concentrations (from 0.01 percent to 0.013 percent) of chromium (VI) oxide solution. Chromium(VI) oxide was applied in both homozygotes and heterozygotes. Chromium (VI) oxide caused prolongation of the period of preadult development in both homozygous and heterozygous progeny in comparison with the untreated group, with a direct correlation to increasing concentration of chromium oxide solution. We hypothesize that chromium (VI) oxide causes dominant mutation(s) on the second chromosome that control the duration of D.melanogaster preadult development.