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CHROMIUM (VI) OXIDE ‐ CrO3 ‐ TREATMENT CAUSES EYELESS (ey) AND SMALL EYE (sey) INDIVIDUALS OF D. melanogaster
Author(s) -
Bajraktari Ismet Dervish,
Alija Avdulla J.,
Muharremi Hidajete S.,
Halili Fetah M.,
Gashi Agim M.,
Bojaxhiu Ekramije M.,
Selmani Shahindere A.,
Halili Shkelzen B.
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a642-a
Subject(s) - chromium , drosophila melanogaster , genetics , oxide , heterozygote advantage , chromosome , recombination , phenotype , biology , chemistry , genotype , materials science , metallurgy , gene
We investigated the effect of chromium (VI) oxide (CrO3) under laboratory conditions on genetic changes of wild type D. melanogaster. The second chromosome of wild type flies was isolated and transferred either in homozygous ( +’ / +’ ) or heterozygous ( +’ / +’’ ) state using the Cy/Pm line. Individuals of this line contain dominant mutations (Cy – Curly wings and Pm – Plum eyes) and long inversions, which prevent recombination with analysed chromosomes, with the end result of stable heredity in the descendants. The +/Cy flies were fed a 0.01 percent solution of chromium(VI) oxide. Chromium (VI) oxide solution was appliedin both homozygotes (+’/Cy x +’/Cy) and heterozygotes (+’/Cy x +’’/Cy). The results showed that chromium oxide treatment caused eyeless (ey) and small eyes (sey) phenotypes in some individuals.