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Effects of Dietary Phytate and Supplemental Zinc on Exchangeable Zinc Pool Mass in Young and Elderly Korean Women
Author(s) -
Kim Jihye,
Paik Hee Young,
Joung Hyojee,
Woodhouse Leslie,
King Janet
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a628
Subject(s) - zinc , chemistry , food science , zoology , biology , organic chemistry
The exchangeable zinc pool (EZP) has been proposed as a zinc status measure. This study was done to determine the effects of dietary phytate (P) and supplemental Zn on EZP size in young and elderly Korean women. Thirteen young (20–24y) and 12 elderly women (64–75y) were studied for three metabolic periods (MP). In MP 1, the women consumed a high phytate (HP) diet (P: Zn molar ratio=23); in MP 2 a low phytate (LP) diet (P: Zn molar ratio=10) was fed, and in MP 3 the women took a 22 mg/d Zn supplement for 27 days while consuming their usual diets. A zinc stable isotope, 70 Zn, was given intravenously on d 5 in MP 1 and 2, and on d 20 in MP 3. Plasma samples were collected after isotope administration for measuring isotopic ratios by Inductively Coupled Plasma (ICP) Mass Spectrometry and PZn concentrations by ICP Emission Spectrometry. EZP was calculated using the method of Miller et al ( J Nutr 1994; 124 :–76). Dietary phytate did not alter PZn or EZP in either group. Supplemental Zn increased PZn and EZP in the young, but had no effect in elderly women. This suggests that PZn and EZP are not sensitive markers of zinc status in older individuals. Supported by Korea Research Foundation and the USDA/ARS WHNRC