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Assessment of Vitamin B6 Status in Korean Patients with Newly Diagnosed Type 2 Diabetes
Author(s) -
CHO YOUNOK,
AHN HEE JUNG,
MIN KYUNG WAN
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a607
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , pyridoxal , vitamin b6 , vitamin , calorie , endocrinology , vitamin c , gastroenterology , metabolic control analysis , chemistry , phosphate , biochemistry
The purpose of this study was to assess vitamin B6 intake and status in Korean patients with newly diagnosed type 2 diabetes. Sixty‐four patients with newly diagnosed type 2 diabetes and with 8–11% A1C and 28 age, sex‐matched control subjects were participated. The dietary vitamin B6 intake and food sources were estimated with 24hour recall method and plasma pyridoxal‐5‐phosphate (PLP) was measured. There was no significant difference in daily total calorie intake between diabetes and control group (1928¡¾402 vs. 2092¡¾765kcal). There was no significant difference in daily total calorie intake between diabetes and control group (2.56 ¡¾0.92 mg/d vs. 2.62 ¡¾0.93mg/d). Plasma PLP levels in diabetic patients tended to be lower than that of control subjects although this difference was not statistically significant due to the large standard deviation (80.0¡¾61.3 nmol/L vs. 68.6¡¾38.6 nmol/L). No significant correlation was found between plasma PLP level and the intakes of total vitamin B6, vitamin B6/1000kcal and vitamin B6/protein in diabetic patients. These data show that plasma PLP levels in diabetic patients tended to be lower than that of control subjects although there was no difference in vitamin B6 intake. Therefore, plasma PLP levels should be monitored in pre‐diabetic patients with diabetic risk factors