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Validation of a Hand‐Held Indirect Calorimeter to Measure Resting Energy Expenditure in Obese Women
Author(s) -
Dobratz Jenny,
Sibley Shalamar,
Beckman Tiffany,
Kellogg Todd,
Ikramuddin Sayeed,
Earthman Carrie
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a588-a
Subject(s) - resting energy expenditure , respiratory quotient , medicine , basal metabolic rate , cart , energy expenditure , limits of agreement , mean difference , zoology , nuclear medicine , biology , mechanical engineering , confidence interval , engineering
Resting energy expenditure (REE) assessment in obese individuals is difficult without a metabolic cart. Hand‐held indirect calorimeters hold promise as practical, inexpensive tools for clinical assessment. In this analysis, REE measurements by a MedGem (MG; HealtheTech, Inc.) hand‐held device and a Deltatrac (DT; VIASYS Healthcare, Inc., SensorMedics) metabolic cart were compared in nine obese women (age 47 +/− 2.9 y; BMI 47.9 +/− 2.1 kg/m‐squared; mean +/− standard error), enrolled in a longitudinal study of metabolic changes after gastric bypass surgery. Only pre‐operative measurements were included in this analysis. REE measurements were made in random order, after an overnight 12‐h fast and a 30‐min rest period at the University of Minnesota General Clinical Research Center. MG‐REE was not different from DT‐REE (mean difference 100.33 +/− 83.8 kcal/d, or mean bias of 5.4%; P =0.265); however, only 56% of subjects (n = 5) had MG‐REE values that fell within +/− 10% of the DT‐REE values, with the other four having values ranging from 83% to 127% of the DT‐REE. Bland‐Altman analysis of the two methods showed wide limits of agreement (+/− 2 standard deviations from the mean bias). Corrections of REE for TUN excretion and respiratory quotient did not alter these findings. In conclusion, the clinical applicability of the MG device cannot be confirmed by these preliminary data. Support was provided by the ASPEN Rhoads Research Foundation of the American Society for Parenteral and Enteral Nutrition and by grant MO1‐RR00400 from the National Center for Research Resources, the National Institutes of Health.