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Metabolic Syndrome and Weight Status in Low‐income obese/overweight Women in Early Postpartum
Author(s) -
Lu Hongxing,
Cahill Jodi M,
Sanghani Bijal V,
Kitchen Jacqueline F,
Bose Tanushee,
FreelandGraves Jeanne H
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a577-b
Subject(s) - overweight , medicine , metabolic syndrome , obesity , environmental health , low income , obstetrics , endocrinology , socioeconomics , economics
Metabolic syndrome includes a cluster of risk factors for heart disease and type 2 diabetes, with obesity being the most important contributor. The purpose of this research is to discern the response of the components of metabolic syndrome to weight change in low‐income, overweight/obese women in early postpartum. Women with 1–4 months old infants were offered weight loss classes for 8 weeks. Weight, height, waist circumference, blood pressure, blood lipids, and insulin were measured before and after the intervention. Metabolic syndrome was defined by the NCEP‐ATP III guidelines. The incidence of metabolic syndrome declined from pre‐ to post‐study (36% vs. 11.4%) as indicated by hypertension (7.8% vs. 0), central obesity (74.5% vs. 58.5%), low HDL (41.2% vs. 25%), hypertriglyceridemia (34.6% vs. 21.2%), and hyperglycemia (34.0% vs. 20.5%) (p<0.05). Improvements also were observed in body mass index (BMI) (31.52 ±5.33 mg/dl vs. 30.38±5.61 mg/dl), serum total cholesterol (210 ±41.0 mg/dl vs. 186±37.3 mg/dl), LDL (127±36.4 mg/dl vs. 110±35.3 mg/dl), and insulin resistance (HOMA) (2.33±2.0 vs. 1.57±1.26) (p<0.01). BMI and insulin resistance strongly correlated with metabolic syndrome (r=0.465 and r=0.438 respectively, P<0.01) and were the best predictors (28% and 16%, respectively) at both pre and post‐study. Modest weight loss in these low‐income women appears to be effective in reducing the risk factors of metabolic syndrome. Supported by TX Coordination Board, # UTA00–377.