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Micronutrient Sprinkles are effective at reducing anemia among children 6–24 months in rural Haiti
Author(s) -
Me Purnima,
Ruel Marie T,
Loechl Cornelia U.,
Arimond Mary,
Habicht JeanPierre,
Pelto Gretel
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a556-c
Subject(s) - micronutrient , medicine , anemia , hemoglobin , context (archaeology) , folic acid , pediatrics , biology , paleontology , pathology
We evaluated the effectiveness of 2‐mo of Sprinkles containing 12.5 mg of Fe, 5 mg Zn, 400 mcg Vit A, 160 mcg folic acid and 30 mg Vit C in reducing anemia (hemoglobin (Hb) <10 g/dL) in children 6 to 20 mo at baseline. Groups of children receiving take‐home rations of fortified wheat‐soy blend (WSB) in the context of a maternal and child health and nutrition program were randomized to receive (S‐WSB) (N=254) or not receive (WSB) (N=161) 30 sachets of Sprinkles for 2 months. At baseline, 53% of S‐WSB children and 37% of WSB children were anemic (p<0.05). At endline, anemia dropped to 29% in S‐WSB (p=0.00), and increased to 45% (p=0.07) in WSB (p=0.00 for differences in before/after change). Mean endline Hb, adjusted for baseline Hb, age and sex, was higher in the S‐WSB group than the WSB group (p=0.00). Mean Hb increased by +0.5 g/dL in the S‐WSB group (p=0.00), and declined by −0.2 g/dL in the WSB group (p=0.00). Changes in Hb were largest in youngest compared to oldest children (adjusted diff.= +1.08 and +0.10 between treatment groups for children 6–8.9 mo and 18–20.9 mo at baseline respectively). Effects were also greatest (+0.85 g/dL) among children who were anemic at baseline. The results show that 2 mo of micronutrient Sprinkles are effective in improving Hb levels and reducing anemia in populations with a high prevalence of anemia, such as rural Haiti. A companion abstract (Loechl et al) also demonstrates the feasibility of this delivery system for Sprinkles. [Support: Micronutrient Initiative, World Vision‐Haiti, Govt. of Germany; USAID through FANTA/AED]