Premium
Development of international nutrient risk assessment model for upper levels of intake
Author(s) -
Taylor Christine Lewis
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a549-b
Subject(s) - harmonization , risk assessment , terminology , agriculture , environmental health , scientific literature , hazard , scientific consensus , hazard analysis , environmental planning , risk analysis (engineering) , business , medicine , geography , engineering , computer science , biology , climate change , ecology , paleontology , linguistics , philosophy , physics , computer security , acoustics , global warming , aerospace engineering
Risk assessment approaches for nutrient substances are becoming increasingly important internationally, especially for establishing upper levels of intake. The Food and Agriculture Organization (FAO) and World Health Organization (WHO) convened a scientific technical workshop in 2005 during which participants outlined an international model for conducting nutrient risk assessment. Model development took into account existing national approaches and classic risk assessment techniques used for other substances found in food. Hazard identification and characterization, estimation of dietary intake or ’exposure,’ and risk characterization were major topics. Participants discussed terminology, identified areas in need of research, and considered the approach for such risk assessment within inadequately nourished populations. The importance of elucidating homeostatic mechanisms for nutrient substances and clarifying the nature of adverse health effects was emphasized. The workshop outcomes will be useful to FAO/WHO in developing future scientific advice about upper levels of intake, but the identified principles may also be helpful to national/regional risk assessors and may encourage international harmonization. Moreover, the availability of such guiding principles could provide a scientific basis for discussing disagreements, if and when they occur, as to conclusions reached about the risk of nutrient substances.