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Educational Resources for Structural Biology at the RCSB Protein Data Bank
Author(s) -
Dutta Shuchismita,
Milton Jeff,
Zardecki Christine,
Berman Helen M
Publication year - 2006
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.20.4.a541-d
Subject(s) - protein data bank (rcsb pdb) , protein data bank , computer science , function (biology) , structural bioinformatics , computational biology , bioinformatics , world wide web , biology , protein structure , genetics , biochemistry
The molecular structures housed in the Protein Data Bank (PDB) range from small pieces of protein or DNA to complex machines such as viruses and ribosomes. Each molecule plays a role in at least one biological process and has value in helping scientists unravel the mysteries of life. Their structures provide insight into these molecules’ roles in fundamental biological processes and, in some cases, into their possible roles in disease or drug interactions. Understanding what these structures look like and being able to ‘see’ how they bind to various ligands greatly aids in understanding how they function. The RCSB PDB‐developed resources for challenging students to explore structure and the tools to examine the relationship of structure to protein function will be discussed. The RCSB PDB ( www.pdb.org ) is operated by Rutgers, The State University of New Jersey and the San Diego Supercomputer Center at the University of California, San Diego, and is supported by funds from supported by funds from the NSF, NIGMS, the Office of Science, DOE, NLM, NCI, NCRR, NIBIB, and NINDS. The RCSB PDB is a member of the wwPDB.