Prevalence of Clostridium difficile and its toxins in hospital patients with diarrhoeal diseases in Lusaka, Zambia | Zendy

Shepherd Nehanda | Zendy; Gina Mulundu | Zendy; Paul Kelly | Zendy

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Prevalence of Clostridium difficile and its toxins in hospital patients with diarrhoeal diseases in Lusaka, Zambia

Author(s) -

Shepherd Nehanda,

Gina Mulundu,

Paul Kelly

Publication year - 2019

Publication title -

transactions of the royal society of tropical medicine and hygiene

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.725

H-Index - 105

eISSN - 1878-3503

pISSN - 0035-9203

DOI - 10.1093/trstmh/trz074

Subject(s) - clostridium difficile , medicine , diarrhoeal disease , latex fixation test , shigellosis , diarrhea , incidence (geometry) , microbiology and biotechnology , clostridium difficile toxin a , shigella , virology , antibiotics , salmonella , immunology , biology , bacteria , genetics , physics , antibody , optics

Clostridium difficile infection (CDI) has emerged as an important nosocomial and antibiotic-associated diarrhoeal problem leading to increasing morbidity and mortality, especially in resource-privileged regions. CDI varies in incidence, pathogenicity and risk factors across geographical locations, yet little information is available on CDI in sub-Saharan Africa. This study aimed to determine the prevalence of Clostridium difficile and related toxin expression in stool specimens from patients with diarrhoeal disease at the University Teaching Hospital, Lusaka, Zambia.

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