Open AccessCRISPRthripsis: The Risk of CRISPR/Cas9-induced Chromothripsis in Gene Therapy
Author(s) -
Mario Amendola,
Mégane Brusson,
Annarita Miccio
Publication year - 2022
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.1093/stcltm/szac064
Subject(s) - chromothripsis , crispr , biology , cas9 , genetics , genome editing , chromosome engineering , chromosome , computational biology , gene , dna , genome instability , dna damage
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