Efficacy of Transcranial Direct Current Stimulation to Improve Insight in Patients With Schizophrenia: A Systematic Review and Meta-analysis of Randomized Controlled Trials | Zendy

Ondine Adam | Zendy; Martin Blay | Zendy; André R. Brui | Zendy; HsinAn Chang | Zendy; July Silveira Gomes | Zendy; Daniel C. Javitt | Zendy; Do-Un Jung | Zendy; Joshua T. Kantrowitz | Zendy; Sanne Koops | Zendy; JeanPierre Lindenmayer | Zendy; Ulrich Palm | Zendy; Robert C. Smith | Zendy; Iris E. Sommer | Zendy; Leandro do Costa Lane Valiengo | Zendy; Thomas W. Weickert | Zendy; Jérôme Brunelin | Zendy; Marine Mondino | Zendy

Open Access

Efficacy of Transcranial Direct Current Stimulation to Improve Insight in Patients With Schizophrenia: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Author(s) -

Ondine Adam,

Martin Blay,

André R. Brui,

HsinAn Chang,

July Silveira Gomes,

Daniel C. Javitt,

Do-Un Jung,

Joshua T. Kantrowitz,

Sanne Koops,

JeanPierre Lindenmayer,

Ulrich Palm,

Robert C. Smith,

Iris E. Sommer,

Leandro do Costa Lane Valiengo,

Thomas W. Weickert,

Jérôme Brunelin,

Marine Mondino

Publication year - 2022

Publication title -

schizophrenia bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.823

H-Index - 190

eISSN - 1745-1707

pISSN - 0586-7614

DOI - 10.1093/schbul/sbac078

Subject(s) - transcranial direct current stimulation , positive and negative syndrome scale , schizophrenia (object oriented programming) , meta analysis , randomized controlled trial , psychology , strictly standardized mean difference , brain stimulation , transcranial magnetic stimulation , medicine , clinical psychology , psychiatry , psychosis , stimulation

Impaired insight into the illness and its consequences is associated with poor outcomes in schizophrenia. While transcranial direct current stimulation (tDCS) may represent a potentially effective treatment strategy to relieve various symptoms of schizophrenia, its impact on insight remains unclear. To investigate whether tDCS would modulate insight in patients with schizophrenia, we undertook a meta-analysis based on results from previous RCTs that investigated the clinical efficacy of tDCS. We hypothesize that repeated sessions of tDCS will be associated with insight improvement among patients.

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