Open AccessTracking mood fluctuations with functional network patterns
Author(s) -
Nykan Mirchi,
Richard F. Betzel,
Boris C. Bernhardt,
Alain Dagher,
Bratislav Mišić
Publication year - 2018
Publication title -
social cognitive and affective neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.229
H-Index - 103
eISSN - 1749-5024
pISSN - 1749-5016
DOI - 10.1093/scan/nsy107
Subject(s) - mood , psychology , default mode network , cognitive psychology , resting state fmri , functional connectivity , neuroscience , anterior cingulate cortex , functional magnetic resonance imaging , developmental psychology , clinical psychology , cognition
Subjective mood is a psychophysiological property that depends on complex interactions among the central and peripheral nervous systems. How network interactions in the brain drive temporal fluctuations in mood is unknown. Here we investigate how functional network configuration relates to mood profiles in a single individual over the course of 1 year. Using data from the 'MyConnectome Project', we construct a comprehensive mapping between resting-state functional connectivity (FC) patterns and subjective mood scales using an associative multivariate technique (partial least squares). We report three principal findings. First, FC patterns reliably tracked daily fluctuations in mood. Second, positive mood was marked by an integrated architecture, with prominent interactions between canonical resting-state networks. Finally, one of the top-ranked nodes in mood-related network reconfiguration was the subgenual anterior cingulate cortex, an area commonly associated with mood regulation and dysregulation. Altogether, these results showcase the utility of highly sampled individual-focused data sets for affective neuroscience.