Open AccessPersistent Post-Mastectomy Pain: The Impact of Regional Anesthesia Among Patients with High vs Low Baseline Catastrophizing
Author(s) -
Nantthasorn Zinboonyahgoon,
Megan Patton,
Yun-Yun K. Chen,
Richard E. Edwards,
Kristin L. Schreiber
Publication year - 2021
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnab039
Subject(s) - medicine , psychosocial , pain catastrophizing , gee , generalized estimating equation , physical therapy , mastectomy , observational study , opioid , anesthesia , chronic pain , psychiatry , breast cancer , statistics , receptor , mathematics , cancer
Persistent post-mastectomy pain (PPMP) varies both in its severity and impact, with psychosocial factors such as catastrophizing conferring greater risk. Preoperative regional anesthesia (RA) is an important nonopioid therapy, but with variable success at preventing PPMP in previous reports. We previously reported that RA was associated with lower acute post-mastectomy pain and opioid use, but more prominently among patients with higher baseline catastrophizing. The current longitudinal investigation at 3, 6, and 12 months postop aimed to detect differential long-term impact of RA on PPMP among patients with high vs low catastrophizing.