Open AccessIntracranial Atherosclerosis: A Disease of Functional, not Anatomic Stenosis? How Trans-Stenotic Pressure Gradients Can Help Guide Treatment
Author(s) -
Mario Zanaty,
James D. Rossen,
Jorge A Roa,
Daichi Nakagawa,
Joseph S. Hudson,
Sami Al Kasab,
Kaustubh Limaye,
Khaled Asi,
Sudeepta Dandapat,
Pascal Jabbour,
Edgar A Samaniego,
David Hasan
Publication year - 2019
Publication title -
operative neurosurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 21
eISSN - 2332-4260
pISSN - 2332-4252
DOI - 10.1093/ons/opz335
Subject(s) - medicine , stenosis , icad , cardiology , lumen (anatomy) , internal carotid artery , radiology , hemodynamics , chemistry , gene , biochemistry
Most trials have assessed intracranial atherosclerotic disease (ICAD) severity based on angiographic stenosis. However, anatomic stenosis might not accurately identify the actual state of functional post-stenotic flow limitation.