Open AccessEndoscopic Transorbital Approach to Mesial Temporal Lobe for Intra-Axial Lesions: Cadaveric Study and Case Series (SevEN-008)
Author(s) -
Hun Ho Park,
Tai Suk Roh,
Seonah Choi,
Jihwan Yoo,
Woo Hyun Kim,
In-Ho Jung,
In Sik Yun,
Chang-Ki Hong
Publication year - 2021
Publication title -
operative neurosurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 21
eISSN - 2332-4260
pISSN - 2332-4252
DOI - 10.1093/ons/opab319
Subject(s) - medicine , neurovascular bundle , cadaveric spasm , middle cranial fossa , temporal lobe , canthus , anatomy , endoscope , trephine , temporal bone , orbit (dynamics) , cerebellopontine angle , surgery , radiology , eyelid , magnetic resonance imaging , epilepsy , psychiatry , engineering , aerospace engineering
BACKGROUND Endoscopic transorbital approach (ETOA) has been proposed as a minimally invasive technique for the treatment of skull base lesions located around mesial temporal lobe (MTL), mostly extra-axial pathology. OBJECTIVE To explore the feasibility of ETOA in accessing intraparenchymal MTL with cadaveric specimens and describe our initial clinical experience of ETOA for intra-axial lesions in MTL. METHODS Anatomic dissections were performed in 4 adult cadaveric heads using a 0° endoscope. First, a stepwise anatomical investigation of ETOA to intraparenchymal MTL was explored. Then, ETOA was applied clinically for 7 patients with intra-axial lesions in MTL, predominantly high-grade gliomas (HGGs) and low-grade gliomas (LGGs). RESULTS The extradural stage of ETOA entailed a superior eyelid incision followed by orbital retraction, drilling of orbital roof, greater and lesser wing of sphenoid bone, and cutting of the meningo-orbital band. For the intradural stage, the brain tissue medial to the occipito-temporal gyrus was aspirated until the temporal horn was opened. The structures of MTL could be aspirated selectively in a subpial manner without injury to the neurovascular structures of the ambient and sylvian cisterns, and the lateral neocortex. After cadaveric validation, ETOA was successfully performed for 4 patients with HGGs and 3 patients with LGGs. Gross total resection was achieved in 6 patients (85.7%) without significant surgical morbidities including visual field deficits. CONCLUSION ETOA provides a logical line of access for intra-axial lesions in MTL. The safe and natural surgical trajectory of ETOA can spare brain retraction, neurovascular injury, and disruption of the lateral neocortex.