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Real-World Efficacy and Tolerability of Brigatinib in Patients with Non-Small Cell Lung Cancer with Prior ALK-TKIs in the United States
Author(s) -
Mohammad Jahanzeb,
Huamao Mark Lin,
Yanyu Wu,
Pingkuan Zhang,
Magdaliz Gorritz,
Catherine B. McGuiness,
WeiTi Huang,
Kainan Sun,
ChiChang Chen,
D. Ross Camidge
Publication year - 2022
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1093/oncolo/oyac116
Subject(s) - crizotinib , alectinib , medicine , discontinuation , tolerability , anaplastic lymphoma kinase , ceritinib , lung cancer , oncology , adverse effect , malignant pleural effusion
Real-world evidence for brigatinib, a next-generation anaplastic lymphoma kinase-tyrosine kinase inhibitor (ALK-TKI) used in ALK-rearranged non-small cell lung cancer, is scarce. This retrospective study evaluated real-world brigatinib utilization in the US post other ALK-TKIs.

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