Estimation of the Incidence of Guillain-Barré Syndrome During Pregnancy in the United States | Zendy

Tanya R. Myers | Zendy; Natalie McCarthy | Zendy; Lakshmi Panagiotakopoulos | Zendy; Saad B. Omer | Zendy

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Estimation of the Incidence of Guillain-Barré Syndrome During Pregnancy in the United States

Author(s) -

Tanya R. Myers,

Natalie McCarthy,

Lakshmi Panagiotakopoulos,

Saad B. Omer

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz071

Subject(s) - guillain barre syndrome , medicine , incidence (geometry) , pregnancy , confidence interval , vaccination , pediatrics , zika virus , obstetrics , immunology , physics , biology , optics , genetics , virus

Guillain-Barré syndrome (GBS) is an adverse event of interest after vaccination, yet few data are available for background rates during pregnancy. We confirmed 2 cases of incident GBS and estimated an incidence of 2.8 confirmed GBS cases per million person-years (95% confidence interval, 0.5–9.3), indicating rare occurrence. Our findings will help inform safety assessments of Zika vaccines in pregnant populations.

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