Open Access1790Targeting filarial kinases with human homologues: repurposed, orally available, approved tyrosine kinase inhibitors (TKI) act as micro- and macrofilaricidal agents at concentrations easily achievable in vivo
Author(s) -
Elise M. O’Connell,
Sasisekhar Bennuru,
Cathy Steel,
Thomas B. Nutman
Publication year - 2014
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofu051.162
Subject(s) - medicine , tyrosine kinase , pharmacology , kinase , in vivo , orally active , oral administration , microbiology and biotechnology , biology , receptor
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