Open AccessProspective Clinical Assessments of Hospitalized Patients With Positive SARS-CoV-2 PCR Tests for Necessity of Isolation
Author(s) -
Chanu Rhee,
Meghan Baker,
Sanjat Kanjilal,
Robert Tucker,
Vineeta Vaidya,
Amy Badwaik,
Elizabeth Mermel Blaeser,
Cassie Coughlin,
Jennifer Elloyan,
Candace Hsieh,
Meghan Holtzman,
Ofelia Solem,
Michael Klompas
Publication year - 2021
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofab194
Subject(s) - medicine , covid-19 , isolation (microbiology) , pcr test , prospective cohort study , transmission (telecommunications) , coronavirus , intensive care medicine , polymerase chain reaction , virology , outbreak , disease , bioinformatics , biochemistry , chemistry , gene , infectious disease (medical specialty) , electrical engineering , biology , engineering
We prospectively assessed 536 hospitalized patients with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction tests for infectiousness based on symptoms, cycle thresholds, and SARS-CoV-2 history, with repeat testing and serologies in select cases. One hundred forty-eight (28%) patients were deemed noninfectious, most with evidence of prior infection, and managed on standard precautions without evidence of transmission.