Open AccessClinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
Author(s) -
Carlos Rocha Oliveira,
Christopher Massad,
Eugene D. Shapiro,
Marietta Vázquez
Publication year - 2021
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofab142
Subject(s) - lyme disease , medicine , lyme , immunology , virology , borrelia burgdorferi , antibody
We conducted a matched case–control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.