Incident Tuberculosis Diagnoses in Children at High Risk for Disease | Zendy

Milagros Wong | Zendy; Julia Coit | Zendy; Milagros Mendoza | Zendy; Silvia S. Chiang | Zendy; Helen Stephani Marin Samanez | Zendy; Jerome T. Galea | Zendy; Leonid Lecca | Zendy; Molly F. Franke | Zendy

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Incident Tuberculosis Diagnoses in Children at High Risk for Disease

Author(s) -

Milagros Wong,

Julia Coit,

Milagros Mendoza,

Silvia S. Chiang,

Helen Stephani Marin Samanez,

Jerome T. Galea,

Leonid Lecca,

Molly F. Franke

Publication year - 2021

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofab075

Subject(s) - medicine , pulmonologist , tuberculosis , medical diagnosis , pediatrics , disease , family medicine , intensive care medicine , pathology

We followed 35 children meeting a research definition for unconfirmed tuberculosis (TB) but in whom a pediatric pulmonologist did not diagnose or treat TB. After a median follow-up of 16.4 months, most children were not diagnosed with TB following a comprehensive evaluation. However, 2 were diagnosed with TB, demonstrating high TB risk (6%; exact 95% CI, 1%–19%). In some contexts, researchers may wish to supplement these research definitions with clinical decision data and longitudinal follow-up in order to improve specificity.

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