Reliability of mecA in Predicting Phenotypic Susceptibilities of Coagulase-Negative Staphylococci and Staphylococcus aureus | Zendy

Ma C. Williams | Zendy; Samuel R. Dominguez | Zendy; Andrea M. Prinzi | Zendy; Kayla Lee | Zendy; Sarah K. Parker | Zendy

Open Access

Reliability of mecA in Predicting Phenotypic Susceptibilities of Coagulase-Negative Staphylococci and Staphylococcus aureus

Author(s) -

Ma C. Williams,

Samuel R. Dominguez,

Andrea M. Prinzi,

Kayla Lee,

Sarah K. Parker

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa553

Subject(s) - coagulase , staphylococcus aureus , sccmec , cons , microbiology and biotechnology , staphylococcus , medicine , methicillin resistant staphylococcus aureus , biology , genetics , bacteria , computer science , programming language

The mecA gene is commonly used to identify resistance in Staphylococcus aureus, but historically is not used for coagulase-negative staphylococci (CoNS). Analysis of 412 staphylococcal blood cultures (2014–2018) revealed that the absence of mecA had high concordance (100%) with oxacillin susceptibility for S. aureus and CoNS alike.

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