Antimicrobial Management of Respiratory Infections in Severe Acute Respiratory Syndrome Coronavirus 2 Patients: Clinical and Antimicrobial Stewardship Programs Conundrums | Zendy

Ellie J. C. Goldstein | Zendy; Glenn Tillotson | Zendy; Mark Redell | Zendy

Open Access

Antimicrobial Management of Respiratory Infections in Severe Acute Respiratory Syndrome Coronavirus 2 Patients: Clinical and Antimicrobial Stewardship Programs Conundrums

Author(s) -

Ellie J. C. Goldstein,

Glenn Tillotson,

Mark Redell

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofaa517

Subject(s) - medicine , antimicrobial stewardship , antimicrobial , intensive care medicine , coinfection , context (archaeology) , coronavirus , antibiotics , respiratory system , covid-19 , antibiotic resistance , immunology , microbiology and biotechnology , infectious disease (medical specialty) , virus , disease , biology , paleontology

The role of empirical and even directed antimicrobial management of patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is problematic; antibiotics are used frequently among these patients to treat confirmed or suspected coinfection or just the symptoms. In the rapidly changing clinical landscape of SARS-CoV-2, there is minimal guidance for selecting appropriate treatment versus non-antimicrobial treatment, and clinicians are pressed to make daily decisions under the stress of absence of data while watching patients deteriorate. We review current data and patterns of antimicrobial use and the potential approach for antimicrobial stewardship in the context of SARS-CoV-2.

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