Open AccessDevelopment of Mycobacterium avium Complex Lung Disease in Patients With Lung Cancer on Immune Checkpoint Inhibitors
Author(s) -
Kohei Fujita,
Yuki Yamamoto,
Osamu Kanai,
Misato Okamura,
Koichi Nakatani,
Tadashi Mio
Publication year - 2020
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofaa067
Subject(s) - medicine , lung cancer , immunotherapy , immune system , tuberculosis , mycobacterium tuberculosis , immunology , mycobacterium avium complex , disease , lung , pathology
Immunotherapy with immune checkpoint inhibitors (ICIs), while ameliorating lung cancer, can cause infectious diseases, including tuberculosis, in addition to immune-related noninfectious complications. In the clinical setting, the efficacy of ICIs to treat mycobacterial infection remains controversial. We report 3 cases of acute Mycobacterium avium complex lung disease during immunotherapy with ICIs.