Genetic and Depressive Traits Moderate the Reward-Enhancing Effects of Acute Nicotine in Young Light Smokers | Zendy

Alexis E. Whitton | Zendy; Norka E. Rabinovich | Zendy; John D. Lindt | Zendy; Michele L. Pergadia | Zendy; Diego A. Pizzagalli | Zendy; David G. Gilbert | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Genetic and Depressive Traits Moderate the Reward-Enhancing Effects of Acute Nicotine in Young Light Smokers

Author(s) -

Alexis E. Whitton,

Norka E. Rabinovich,

John D. Lindt,

Michele L. Pergadia,

Diego A. Pizzagalli,

David G. Gilbert

Publication year - 2021

Publication title -

nicotine and tobacco research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.338

H-Index - 113

eISSN - 1469-994X

pISSN - 1462-2203

DOI - 10.1093/ntr/ntab072

Subject(s) - nicotine , placebo , allele , psychology , big five personality traits , smoking cessation , medicine , personality , psychiatry , genetics , biology , social psychology , alternative medicine , pathology , gene

Rates of light smoking have increased in recent years and are associated with adverse health outcomes. Reducing light smoking is a challenge because it is unclear why some but not others, progress to heavier smoking. Nicotine has profound effects on brain reward systems and individual differences in nicotine's reward-enhancing effects may drive variability in smoking trajectories. Therefore, we examined whether a genetic risk factor and personality traits known to moderate reward processing, also moderate the reward-enhancing effects of nicotine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research