Increased mtDNA mutation frequency in oocytes causes epigenetic alterations and embryonic defects
Author(s) -
Longsen Han,
Yujia Chen,
Ling Li,
Chao Ren,
Haichao Wang,
Xinghan Wu,
Juan Ge,
Wenjie Shu,
Minjian Chen,
Qiang Wang
Publication year - 2022
Publication title -
national science review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.433
H-Index - 54
eISSN - 2095-5138
pISSN - 2053-714X
DOI - 10.1093/nsr/nwac136
Subject(s) - biology , epigenetics , mitochondrial dna , reprogramming , dna methylation , genetics , maternal to zygotic transition , oocyte , dna demethylation , embryo , mitochondrion , mitochondrial biogenesis , embryogenesis , andrology , gene , zygote , microbiology and biotechnology , gene expression , medicine
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