Open AccessBilateral Deep Brain Stimulation is the Procedure to Beat for Advanced Parkinson Disease: A Meta-Analytic, Cost-Effective Threshold Analysis for Focused Ultrasound
Author(s) -
Uma V. Mahajan,
Vinod K Ravikumar,
Kevin K. Kumar,
Seul Ku,
Disep I. Ojukwu,
Camilla Kilbane,
Pejman Ghanouni,
Joshua M. Rosenow,
Sherman C. Stein,
Casey H. Halpern
Publication year - 2020
Publication title -
neurosurgery/neurosurgery online
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.455
H-Index - 198
eISSN - 1081-1281
pISSN - 0148-396X
DOI - 10.1093/neuros/nyaa485
Subject(s) - deep brain stimulation , medicine , subthalamic nucleus , cost effectiveness , parkinson's disease , cost–utility analysis , physical medicine and rehabilitation , magnetic resonance imaging , quality of life (healthcare) , functional magnetic resonance imaging , adverse effect , disease , radiology , nursing , risk analysis (engineering)
Parkinson disease (PD) impairs daily functioning for an increasing number of patients and has a growing national economic burden. Deep brain stimulation (DBS) may be the most broadly accepted procedural intervention for PD, but cost-effectiveness has not been established. Moreover, magnetic resonance image-guided focused ultrasound (FUS) is an emerging incisionless, ablative treatment that could potentially be safer and even more cost-effective.