Deep learning-based automatic tumor burden assessment of pediatric high-grade gliomas, medulloblastomas, and other leptomeningeal seeding tumors
Author(s) -
Jian Peng,
Daniel D Kim,
Jay Patel,
Xiaowei Zeng,
Jiaer Huang,
Ken Chang,
Xinping Xun,
Chen Zhang,
John Sollee,
Jing Wu,
Deepa Dalal,
Xue Feng,
Hao Zhou,
Chengzhang Zhu,
Beiji Zou,
Ke Jin,
Patrick Y. Wen,
Jerrold L. Boxerman,
Katherine E. Warren,
Tina Young Poussaint,
Lisa J. States,
Jayashree Kalpathy–Cramer,
Li Yang,
Raymond Y. Huang,
Harrison X. Bai
Publication year - 2021
Publication title -
neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.005
H-Index - 125
eISSN - 1523-5866
pISSN - 1522-8517
DOI - 10.1093/neuonc/noab151
Subject(s) - medicine , magnetic resonance imaging , fluid attenuated inversion recovery , radiology , intraclass correlation , segmentation , nuclear medicine , ependymoma , neurosurgery , artificial intelligence , computer science , clinical psychology , psychometrics
Longitudinal measurement of tumor burden with magnetic resonance imaging (MRI) is an essential component of response assessment in pediatric brain tumors. We developed a fully automated pipeline for the segmentation of tumors in pediatric high-grade gliomas, medulloblastomas, and leptomeningeal seeding tumors. We further developed an algorithm for automatic 2D and volumetric size measurement of tumors.
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