Open AccessDifferences in proximal tubular solute clearance across common etiologies of chronic kidney disease
Author(s) -
Ke Wang,
Leila R. Zelnick,
Andrew N. Hoofnagle,
Yan Chen,
Ian H. de Boer,
Jonathan Himmelfarb,
Bryan Kestenbaum
Publication year - 2019
Publication title -
nephrology, dialysis, transplantation/nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfz144
Subject(s) - medicine , renal function , kidney disease , endocrinology , etiology , urology , confidence interval , kidney
Laboratory measures of glomerular function such as the glomerular filtration rate (GFR) contribute toward clinical evaluation of chronic kidney disease (CKD). However, diverse CKD etiologies have distinct pathological mechanisms that may differentially impact the kidney tubules. Little is known regarding how tubular function changes with varying kidney disease types.