Open AccessHyponatremia and other electrolyte abnormalities in patients receiving immune checkpoint inhibitors
Author(s) -
Harish Seethapathy,
Nifasha Rusibamayila,
Donald F. Chute,
Meghan Lee,
Ian A. Strohbehn,
Leyre Zubiri,
Alexander T. Faje,
Kerry L. Reynolds,
Kenar D. Jhaveri,
Meghan E. Sise
Publication year - 2020
Publication title -
nephrology, dialysis, transplantation/nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfaa272
Subject(s) - hyponatremia , medicine , hypokalemia , hyperkalemia , electrolyte disorder , retrospective cohort study , adverse effect , gastroenterology , pediatrics
Hyponatremia due to endocrinopathies such as adrenal insufficiency and hypothyroidism has been reported in patients receiving immune checkpoint inhibitors (ICIs). We determined the risk and predictors of hyponatremia and other electrolyte abnormalities in a 'real-world' sample of patients receiving ICIs to treat advanced malignancies.