Selection and sequence analysis of a cDNA clone encoding a known chorion protein of the A family
Author(s) -
Sonia G. Tsitilou,
Jerome C. Regier,
Fotis C. Kafatos
Publication year - 1980
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/8.9.1987
Subject(s) - biology , complementary dna , clone (java method) , cdna library , genetics , sequence (biology) , sequence analysis , selection (genetic algorithm) , expressed sequence tag , protein sequencing , nucleic acid sequence , peptide sequence , microbiology and biotechnology , gene , computational biology , artificial intelligence , computer science
Using as criteria the size, abundance and developmental specificity of hybridizing mRNA sequences, we have selected from our chorion cDNA library a clone corresponding to a specific chorion protein, A4--cl. Comparison between the clone sequence and the largely known sequence of A4--cl validates the use of the cDNA library for sequence analysis of the chorion multigene families. The two major chorion protein families, A and B, share certain structural similarities.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom