Open AccessSelection and sequence analysis of a cDNA clone encoding a known chorion protein of the A family
Author(s) -
Sonia G. Tsitilou,
Jerome C. Regier,
Fotis C. Kafatos
Publication year - 1980
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/8.9.1987
Subject(s) - biology , complementary dna , clone (java method) , cdna library , genetics , sequence (biology) , sequence analysis , selection (genetic algorithm) , expressed sequence tag , protein sequencing , nucleic acid sequence , peptide sequence , microbiology and biotechnology , gene , computational biology , artificial intelligence , computer science
Using as criteria the size, abundance and developmental specificity of hybridizing mRNA sequences, we have selected from our chorion cDNA library a clone corresponding to a specific chorion protein, A4--cl. Comparison between the clone sequence and the largely known sequence of A4--cl validates the use of the cDNA library for sequence analysis of the chorion multigene families. The two major chorion protein families, A and B, share certain structural similarities.