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Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type
Author(s) -
Richard Grantham,
Christian Gautier,
Manolo Gouy
Publication year - 1980
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/8.9.1893
Subject(s) - biology , genome , gene , codon usage bias , genetics , variation (astronomy) , degenerate energy levels , coding region , computational biology , physics , quantum mechanics , astrophysics
The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.

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