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We present a preliminary theoretical study of the electrostatic potential surrounding yeast tRNAPhe by computing the component of this potential due to all the 76 phosphate groups of the molecule. The general features of the results obtained are discussed and deductions concerning the binding of Mg2+ ions to the molecule in relation to the potential are presented.

The electrostatic molecular potential of yeast tRNAPhe. (I). The potential due to the phosphate backbone

The electrostatic molecular potential of yeast tRNA^Phe. (I). The potential due to the phosphate backbone