Open AccessMobile dispersed genetic element MDGI of Drosophila melanogaster: structural organization
Author(s) -
Yu. V. Ilyin,
V.G. Chmeliauskate,
E. V. Ananiev,
N. V. Lyubomirskaya,
V.V. Kulguskin,
A.A. Bayev,
Georgii P. Georgiev
Publication year - 1980
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/8.22.5333
Subject(s) - biology , mobile genetic elements , drosophila melanogaster , genome , genetics , melanogaster , retrotransposon , dna , repeated sequence , dna transposable elements , genomic organization , restriction map , transposable element , gene , base sequence
The whole-length mobile dispersed genetic element mdg1 has been cloned from D. melanogaster genome. It contains DNA fragments described earlier as Dm225 and Dm234, Mdg1 is 7.2 kb long and framed with two direct repeats of 300-400 base pairs each. Mdg1 family is represented by about 25 copies in the genome of flies and by 200 copies in the genome of cultured cell line 67J25D. Virtually all the copies in the genome of D. melanogaster have the same restriction map. Oligo(dA)-oligo(dT) regions were found within mdg1.