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Nucleotide sequences of nuclear U1A RNAs from chicken, rat and man
Author(s) -
Christiane Branlant,
Alain Krol,
JeanPierre Ebel,
Eliane Lazar,
Hélène Gallinaro,
Monique Jacob,
Joannés Sri-Widada,
Philippe Jeanteur
Publication year - 1980
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/8.18.4143
Subject(s) - biology , genetics , nucleotide , microbiology and biotechnology , gene
The methods of enzymatic and chemical treatment of end-labeled RNA were applied to the determination of the nucleotide sequence of chicken and man U1A RNA and to the reexamination of that of rat U1A RNA. The chemical method allowed the easy demonstration of the cap structure. All three RNA were 165 nucleotide long. Two hitherto non described modified pyrimidines were detected close to the 5' end. Only 9 base substitutions were observed from chicken to man indicating high degree of conservation of U1A RNA through evolution.

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