Studies on transfer ribonucleic acids and related compounds. XXXII. Synthesis of ribonucleotides corresponding to residues 1-5 and 6-10 of tRNAfMetfrom E.coli and their base conversion analogs | Zendy

Eiko Ohtsuka | Zendy; Toshiki Tanaka | Zendy; Morio Ikehara | Zendy

Open Access

Studies on transfer ribonucleic acids and related compounds. XXXII. Synthesis of ribonucleotides corresponding to residues 1-5 and 6-10 of tRNA^fMetfrom E.coli and their base conversion analogs

Author(s) -

Eiko Ohtsuka,

Toshiki Tanaka,

Morio Ikehara

Publication year - 1979

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/7.5.1283

Subject(s) - guanosine , transfer rna , transversion , biology , nucleotide , base (topology) , stereochemistry , escherichia coli , base pair , biochemistry , rna , dna , gene , chemistry , mutation , mathematical analysis , mathematics

E. Coli tRNAfMet fragments, C-G-C-G-Gp (bases 1-5), U-G-C-G-Gp (base 1 transition, analog) pG-G-C-G-Gp (base 1 transversion analog) and pG-G-s4U-G-Gp (bases 6-10) were synthesized by triester methods using 2'-O-(o-nitrobenzyl) nucleotides including a 3',5'-bisphosphorylated guanosine derivative. The s4U containing pentanucleotide was derived from the pG-G-C-G-Gp by treatment with liquid hydrogen sulfide.

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