RNA-RNA interactions in the binding site of protein L24 on 23S ribosomal RNA of E. coli II. Sequence analysis of the interacting fragments | Zendy

Alain Krol | Zendy; Mohamed Ali Machatt | Zendy; Christiane Branlant | Zendy; J.P. Ebel | Zendy

Open Access

RNA-RNA interactions in the binding site of protein L24 on 23S ribosomal RNA of E. coli II. Sequence analysis of the interacting fragments

Author(s) -

Alain Krol,

Mohamed Ali Machatt,

Christiane Branlant,

J.P. Ebel

Publication year - 1978

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/5.12.4933

Subject(s) - rna , biology , ribonucleoprotein , 23s ribosomal rna , rna editing , base pair , genetics , ribosomal rna , rna binding protein , non coding rna , microbiology and biotechnology , ribosome , dna , gene

A ribonucleoprotein complex containing several RNA subfragments from the 5' part of 23S RNA was recovered after digestion of the reconstituted complex between 23S RNA and protein L24. It was suggested in the preceding paper that the RNA subfragments 4B, 10A and 9, which are widely separated in the sequence, strongly interact. These subfragments were previously partially sequenced by the classical fingerprinting methods. Their sequences have now been completed with rapid new RNA sequencing methods. We propose here a base-pairing model showing how these subfragments may interact with one another.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research