Nucleotide sequence relationships between vertebrate 5.8 S ribosomal RNAs | Zendy

M.S.N. Khan | Zendy; B.E.H. Maden | Zendy

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Nucleotide sequence relationships between vertebrate 5.8 S ribosomal RNAs

Author(s) -

M.S.N. Khan,

B.E.H. Maden

Publication year - 1977

Publication title -

nucleic acids research

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/4.7.2495

Subject(s) - biology , vertebrate , ribosomal rna , sequence (biology) , genetics , nucleic acid sequence , base sequence , evolutionary biology , phylogenetics , computational biology , ribosomal dna , dna , gene

Nucleotide sequences of the 5.8 S ribosomal RNAs from HeLa cells, Xenopus laevis and chick embryo fibroblasts were compared. Xenopus laevis 5.8 S RNA differs from that of HeLa cells in four internal positions and at the 3' end of the molecule. Chick 5.8 S RNA differs from that of HeLa cells in two positions. Six out of the seven interspecies differences are due to base substitutions. The other difference is due to the presence of an extra nucleotide, internally located, within the Xenopus 5.8 S sequence.

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