Open AccessA13C NMR study of poly(adenosine diphosphate ribose) and its monomers: evidence of α-(1″→2′) ribofuranosyl ribofuranoside residue
Author(s) -
Miwa Misawa,
Hazime Saitô,
Harutake Sakura,
Noriko Saikawa,
Fumiko Watanabe,
Taijiro Matsushima,
Takashi Sügimura
Publication year - 1977
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/4.11.3997
Subject(s) - glycosidic bond , ribose , adenosine , residue (chemistry) , stereochemistry , biology , monomer , carbon 13 nmr , nuclear magnetic resonance spectroscopy , biochemistry , enzyme , chemistry , organic chemistry , polymer
The 13C NMR spectra of poly(adenosine diphosphate ribose), ribosyl adenosine 5', 5''-bis(phosphate) and related compounds were analyzed. The structure of the ribose-ribose linkage was determined as alpha-(1'' leads to 2')ribofuranosyl ribofuranoside, from the 13C chemical shifts of methyl-alpha- and methyl-beta-D-ribofuranosides, and from the downfield displacements of 13C NMR signals by glycosidic bond formation.