Open AccessCapping structures of simian virus 40 19S and 16S mRNAs
Author(s) -
Yoram Groner,
Pnina Carmi,
Yosef Aloni
Publication year - 1977
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/4.11.3959
Subject(s) - biology , methylation , messenger rna , rna , microbiology and biotechnology , virus , 16s ribosomal rna , virology , genetics , gene
In vivo [methyl 3H]-labeled SV40 19S and 16S mRNA species were purified and their internal methylation as well as their capping structures analyzed. SV40 viral mRNA sedimenting in the 19S region contains approximately equal proportions of m7GpppAm and m7Gppm6Am, while the 16S mRNA contains mainly m7Gpppm6Am. N6 methyl adenosine is located internally within the RNA chains of both the 19S and 16S species.
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