Open AccessLRG1 is expressed during speculation inSaccharomyces cerevisiaeand contains motifs similar to LIM and rho/racGAP domains
Author(s) -
Liz Girardi Müller,
Gang Xu,
Richard A. Wells,
Cornelis P. Hollenberg,
Wolfgang Piepersberg
Publication year - 1994
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/22.15.3151
Subject(s) - biology , saccharomyces cerevisiae , gene , genetics , peptide sequence , yeast , sequence (biology) , gtpase , microbiology and biotechnology
We here report the sequence of a yeast gene LRG1 whose deduced amino acid sequence contains sequence motifs similar to LIM domain proteins in the amino-terminal, and to rho/rac GTPase activating proteins (rho/racGAP's) in the carboxy-terminal part. LRG1 expression is differentially regulated showing a peak of expression in sporulating cells. Gene disruption experiments indicate that the gene is not essential and may play a role during mating.