Proton NMR studies of manganese ion binding to tRNAderived acceptor arm duplexes | Zendy

Gu nther Ott | Zendy; Lubosˇ Arnold | Zendy; Stefan Limmer | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Proton NMR studies of manganese ion binding to tRNAderived acceptor arm duplexes

Author(s) -

Gu nther Ott,

Lubosˇ Arnold,

Stefan Limmer

Publication year - 1993

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/21.25.5859

Subject(s) - context (archaeology) , manganese , binding site , wobble base pair , acceptor , metal , ion , nuclear magnetic resonance spectroscopy , crystallography , divalent , metal ions in aqueous solution , biology , rna , stereochemistry , materials science , chemistry , transfer rna , biochemistry , physics , paleontology , organic chemistry , gene , condensed matter physics , metallurgy

Several RNA duplexes corresponding to the acceptor arms of different tRNAs have been analyzed with respect to their divalent metal ion binding capability by means of proton NMR spectroscopy using paramagnetic Mn2+ ions as probes. In particular, the role of GU wobble base pairs has been analyzed with reference to their potential for creating metal ion binding sites. It is shown that both the structural modifications induced by GU pairs in the A-RNA geometry and the sequence context seem to affect the metal ion binding capabilities.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research