Sequence and variablity of the 5.8S and 26S rRNA genes ofPneumocystis carinii
Author(s) -
Yong Liu,
Marissa Rocourt,
Sueihua Pan,
Chentzu Liu,
Michael J. Leibowitz
Publication year - 1992
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/20.14.3763
Subject(s) - biology , ribosomal rna , intron , pneumocystis carinii , genetics , gene , homology (biology) , 18s ribosomal rna , group i catalytic intron , 23s ribosomal rna , operon , rna splicing , rna , ribosome , virology , escherichia coli , human immunodeficiency virus (hiv) , pneumocystis jirovecii
The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom