Open AccessSequence and variablity of the 5.8S and 26S rRNA genes ofPneumocystis carinii
Author(s) -
Yong Liu,
Marissa Rocourt,
Sueihua Pan,
Chientzu Liu,
Michael J. Leibowitz
Publication year - 1992
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/20.14.3763
Subject(s) - biology , ribosomal rna , intron , pneumocystis carinii , genetics , gene , homology (biology) , 18s ribosomal rna , group i catalytic intron , 23s ribosomal rna , operon , rna splicing , rna , ribosome , virology , escherichia coli , human immunodeficiency virus (hiv) , pneumocystis jirovecii
The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.