Poly(U, s4U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derived from rat liver | Zendy

M. Keren-Zur | Zendy; Abraham Hochberg | Zendy; Natalia Sánchez de Groot | Zendy; Y. Lapidot | Zendy

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Poly(U, s⁴U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derived from rat liver

Author(s) -

M. Keren-Zur,

Abraham Hochberg,

Natalia Sánchez de Groot,

Y. Lapidot

Publication year - 1975

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/2.4.595

Subject(s) - biology , messenger rna , cell free system , rna , transfer rna , phenylalanine , biochemistry , protein biosynthesis , amino acid , microbiology and biotechnology , enzyme , gene

Two different U and S4-U containing polymers with U:s4U ratio of 3:1 and 5:1 were synthesized. Their activity as messenger RNA was studied in an amino acid incorporation cell-free system from rat liver. It was shown that both copolymers can stimulate the incorporation of phenylalanine into oligophynylalamyl-tRNA.

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