An Xmnl RFLP detected with a probe for the CYP2E gene locus on chromosome 10 | Zendy

David P. Kelsell | Zendy; C. Roland Wolf | Zendy; Nigel K. Spurr | Zendy

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An Xmnl RFLP detected with a probe for the CYP2E gene locus on chromosome 10

Author(s) -

David P. Kelsell,

C. Roland Wolf,

Nigel K. Spurr

Publication year - 1990

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/18.10.3111

Subject(s) - biology , locus (genetics) , genetics , restriction fragment length polymorphism , gene , library science , classics , history , polymerase chain reaction , computer science

Source/Description: A 1.6 Kbp fragment of the cDNA clone for the human ethanol inducible cytochrome P450 gene cloned in pUC18 at the EcoRI restriction site (Song and Gonzalez, 1986). Polymorphism: Xmnl detects a two allele polymorphism with bands at 16 kb (Al), 11.4 and 4.6 kb (A2). Frequency: A total of 37 unrelated individuals of Caucasian origin were screened: Al 0.81; A2 0.19.

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