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Structure and genomic organization of I elements involved in I - R hybrid dysgenesis inDrosophila melamogaster
Author(s) -
Michèle Crozatier,
Chantal Vaury,
Isabclle Busseau,
Alain Pélisson,
Alain Bucheton
Publication year - 1988
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/16.19.9199
Subject(s) - biology , inducer , transposable element , dysgenesis , drosophila melanogaster , genetics , p element , mutation , drosophilidae , genome , gene
I-R hybrid dysgenesis in D. melanogaster is controlled by transposable elements known as I factors which terminate at their 3' ends by an A-rich sequence. Inducer strains contain active I factors. Both reactive and inducer stocks possess defective I elements. We have cloned various I elements from both categories of strains. The I elements having recently transposed in inducer strains have a structure closely related to that of active I factors. However we have isolated one such I element that is truncated at its 5' end. The I elements common to reactive and inducer strains are affected by various rearrangements and many point mutations. They do not appear to be simple derivatives of complete I factors.

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