Chromosome size polymorphism inPlasmodium falciparumcan involve deletions of the subtelomeric pPFrep20 sequence | Zendy

Jintana Patarapotikul | Zendy; Gordon Langsley | Zendy

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Chromosome size polymorphism inPlasmodium falciparumcan involve deletions of the subtelomeric pPFrep20 sequence

Author(s) -

Jintana Patarapotikul,

Gordon Langsley

Publication year - 1988

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/16.10.4331

Subject(s) - biology , subtelomere , genetics , plasmodium falciparum , chromosome , repeated sequence , microbiology and biotechnology , gene , genome , malaria , immunology

The P. falciparum pPFrep20 repetitive element from the Palo Alto Uganda strain has been isolated and sequenced. The Palo Alto pPFrep20 repeat (pPFPArep20) has a clustered subtelomeric location and on chromosome 1 has been deleted from one end. Analysis of chromosome 1 from 5 other strains has revealed that pPFrep20 sequences have been deleted from one end in 3 of them. Thus, deletion of pPFrep20 appears to be a frequent event that could significantly contribute to chromosome size polymorphism in P. falciparum.

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