Open AccessThe relationships between the 5′ end repeats and the largest members of the LI interspersed repeated family in the mouse genome
Author(s) -
Véronique Jubier-Maurin,
Patrick Wincker,
G Cuny,
Gérard Roizès
Publication year - 1987
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/15.18.7395
Subject(s) - biology , tandem repeat , genome , genetics , interspersed repeat , repeated sequence , direct repeat , genomic organization , human genome , gene
Analysis of a few large L1 elements has revealed two types of tandem repeats at the 5' end: A and F. In this study, the relationships between these repeats and a series of large L1 elements has been analysed. Most of cloned L1 repeats were shown to lack either A or F sequences at their 5' ends. F sequences are found less frequently associated than A sequences to the 5' ends of L1 and an evolutionary comparison shows that the A type was introduced more recently during the evolution of the mouse genome than the F type.